Dr. Muhammad Farrukh Nisar
Assistant Professor
Physiology and Biochemistry — Faculty of Biosciences
Biography
Dr. Muhammad Farrukh Nisar is an Assistant Professor in the Department of Physiology and Biochemistry at Cholistan University of Veterinary and Animal Sciences (CUVAS), Pakistan. He earned his Ph.D. in Biomedical Engineering majors in biochemistry and biotechnology from Chongqing University, China in December 2016, and completed Postdoctoral research at Jiangxi Agricultural University (2025). With over eight years of university teaching and research experience, his work focuses on the molecular mechanisms of aging associated disorders (cancer and diabetes) and photomedicine. He has supervised 22 MS students, secured competitive research grants, and published extensively in high-impact journals. Dr. Nisar also serves as a guest editor for several international journals and has received multiple awards for his research presentations.
Research interests
- Natural Anti-Cancer Drugs & Non-Coding RNAs: Investigating small drug molecules
lncRNAs
and microRNAs for cancer therapy.
- Computational Biochemistry: Utilizing molecular docking
simulation
and network pharmacology for drug design and nanomedicine development.
- Cellular Death Mechanisms: Studying apoptosis
autophagy
ferroptosis
NETosis
and ER stress in tumor cells and cancer stem cells.
- Oncology & Cancer Biology: Researching tumorigenesis
tissue engineering
and cell signaling pathways like Nrf2/HO-1.
- Oxidative Stress & Photomedicine: Exploring ROS/RNS biology and the use of UVA phototherapy and chemotherapy for cancer and photoaging.
- Biomedical Materials & Phytochemistry: Developing targeted drug delivery systems and studying natural products and Traditional Chinese Medicine (TCM).
Educational information
| Year | Degree | Board / University |
|---|---|---|
| 2025 | Post Doc | Jiangxi Agricultural University, Nanchang, China |
| 2016 | Ph.D. | Chongqing University, Chongqing, China |
| 2008 | M.Phil. Cell and Molecular Biology | Quaid i Azam University Islamabad, Pakistan |
Academic experience
| From | To | Post held | Organisation |
|---|---|---|---|
| October 2017 | December 2018 | Assistant Professor | Interdisciplinary Research Center in Biomedical Materials (IRCBM), COMSATS University Islamabad, Lahore Campus, Lahore, Pakistan |
Publications
- — Bach transcription factors: Emerging molecular regulators for oxidative stress-mediated skin responses and protection, Journal of Photochemistry and Photobiology B: Biology2026
- — Insulin-like growth factor receptor signaling in physiology and disease, Nature Signal Transduction and Targeted Therapy (Nature STTT) Impact Factor 81.22026
- — Ginkgolide A Suppresses Osteosarcoma Proliferation and Activates the Apoptotic Pathway by Targeting the KAT2A-H3K18la Lactylation Axis, Anti-Cancer Agents in Medicinal Chemistry2026
- — Mechanism of tectorigenin in promoting thermal burn wound healing via the Nrf2-mediated ferroptosis pathway: Integrated pharmacological and experimental study, International Journal of Biological Macromolecules2026
- — An Integrative Bioinformatics and Experimental Approach Identifies a Novel Cell Death Index and Prognostic Biomarkers in Acute Myeloid Leukemia., Journal of King Saud University - Science2025
- — Mechanism of theaflavins inhibiting the proliferation of nasopharyngeal carcinoma cells, Food Science & Nutrition2025
- — Investigating the Antifungal Mechanism of Hinokitiol as a novel antifungal agent: Understanding toxicity towards Geotrichum citri-aurantii and efficacy in controlling citrus sour rot, Phytopathology2025
- — Citri Reticulatae Pericarpium modulates gut microbiota: Impacts on human health, Food Research International2025
- — Ultraviolet radiation induces caspase cleavage and nuclear translocation of heme oxygenase 1 (HO-1) to activate autophagy in skin keratinocytes, The FEBS Journal2025
- — Gastrodin attenuates rheumatoid arthritis by targeting KAT8 to inhibit the lactylation of H3K9, Frontiers in Pharmacology2025
- — Application of artificial intelligence in stem cell therapy and gene therapy of gynecological cancers, Current Stem Cell Research and Therapy2025
- — Notch signaling pathway in osteogenesis, bone development, metabolism, and diseases, The FASEB Journal2025
- — Immuno-oncological challenges and chemoresistance in veterinary medicine: Probiotics as a new strategic tool, Probiotics and Antimicrobial proteins2025
- — Coptis chinensis Franch relies on the anti-inflammatory effect of berberine through the JAK2-STAT3-NF-κB signaling pathway and amino acid metabolism regulation to alleviate stomach heat syndrome, Current Pharmaceutical Design (Q2)2025
- — Pharmacological Aspects and Clinical Implications of Tea (Camellia Sinensis) Bioactive Compounds Against Prostate Cancer, Curr. Res. Nutrition and Food Science2025
- — Nanotechnology-based Delivery Systems for Enhanced Bioavailability of Antioxidant Compounds in Fruits and Vegetables, Curr. Res. Nutrition and Food Science2025
- — Berberine hydrochloride inhibits the proliferation and tumorigenesis of hepatocellular carcinoma cells by regulating amino acid metabolism, Anti-Cancer Agents in Medicinal Chemistry2024
- — Current mechanistic insights into Withaferin A: a promising potential adjuvant anticancer agent from Withania somnifera, Naunyn-Schmiedeberg’s Archives of Pharmacology2024
- — Effective synergism of Moringa oleifera with antibiotics, body growth, and decoction replacement, South African Journal of Botany2024
- — Anti-diabetic Effects of Marine Natural Products Through Redox Modulation via Nrf2/HO-1 Cytoprotective Pathways, Frontiers in Marine Sciences2024
- — Pyrroloquinoline Quinone (PQQ): Exploring its Impact on Human Health and Potential Benefits, Current Research in Food Science2024
- — Targeted therapy of tumors and cancer stem cells based on oxidant-regulated redox pathway and its mechanism, Current Computer Aided Drug Design2024
- — Role of phytochemicals isolated from Cirsium japonicum in neurological disorders, PHYTON Nutrients2024
- — Marine Macrolides: An Indepth Survey of Potential Therapeutic Activities, Journal of Marine Science and Research.2024
- — Water extracts of Polygonum multiflorum Thunb. and its active component emodin relieves osteoarthritis by regulating cholesterol metabolism and suppressing chondrocyte inflammation, Acupuncture and Herbal Medicine2023
- — Eriocitrin: A review of pharmacological effects, Biomedicine and Pharmacotherapy2022
- — Extracellular vesicles and exosomes: An Insight from physiological regulatory perspectives, J. of Physiology & Biochem.2022
- — A Review on Emerging Therapeutic Interventions for Corona Virus, J. Pharma. Res. International2022
- — Pragmatic Applications and Universality of DNA Barcoding for Substantial Organisms at Species Level: A Review to Explore a way Forward, BioMed Research International2022
- — Pharmacological Activities of Natural Products through the TGF-β Signalling Pathway, Evidence-Based Complementary and Alternative Medicine2021
- — Theaflavins chemistry and its health benefits, Oxidative Medicine and cellular longevity2021
- — Eriodictyol protects skin cells from UVA irradiation-induced photodamage by inhibition of the MAPK signaling pathway, Journal of Photochemistry and Photobiology B: Biology2021
- — Investigation on the Phytochemical Composition, Antioxidant and Enzyme Inhibition Potential of Polygonum Plebeium R.Br: A Comprehensive Approach to Disclose New Nutraceutical and Functional Food Ingredients, Chemistry and Biodiversity2021
- — Potential effects of Dietary Isoflavones to Drug-Induced Liver Injury, Journal Of Food Quality2021
- — Revealed pathophysiological mechanisms of crosslinking interaction of affected vital organs in COVID- 19, Comparative Clinical Pathology (Springer)2021
- — Pharmacological Properties and Health Benefits of Eugenol: A Comprehensive Review, Oxidative Medicine and Cellular Longevity2021
- — Biological activities and chemistry of Triterpene Saponins from Medicago species: An update review, Evidence-Based Complementary and Alternative Medicine2021
- — Development of Iron Sequester Antioxidant Quercetin@ZnO Nanoparticles with Photoprotective Effects on UVA-Irradiated HaCaT Cells, Oxidative Medicine and Cellular Longevity2021
- — Bach2 regulates autophagy to modulate UVA-induced photoaging in skin fibroblasts, Free Radical Biology and Medicine2021
- — UVA-Triggered Drug Release and Photo-Protection of Skin, Frontiers Cell and Developmental Biology2021
- — p75NTR and its carboxyl-terminal fragment perform contradictory roles in melanoma cell proliferation and apoptosis via modulation of NF-κB pathway, FEBS Open Bio2020
- — SARS-CoV-2 Microbiome Dysbiosis Linked Disorders and Possible Probiotics Role, Biomedicine & Pharmacotherapy2020
- — Synthesis and antifungal activities of cinnamaldehyde derivatives against Penicillium digitatum causing citrus green mold, Journal of Food Quality2020
- — Surface-modified polymeric nanoparticles for drug delivery to cancer cells, Expert Opinion on Drug delivery2020
- — Light: An alternative method for physical control of postharvest rotting caused by fungi of citrus fruit, Journal of Food Quality2020
- — Chemical Constituents and Health Benefits of Four Chinese Plum Species, Journal of Food Quality2020
- — Anti-inflammatory Constituents from Chaenomeles speciosa, Natural Products Commun.2020
- — Characterization of phenolic constituents from Prunus cerasifera Ldb Leaves, Journal of Chemistry2020
- — Heme Oxygenases: Cellular Multifunctional and Protective Molecule Against UV-induced Oxidative Stress, Oxidative Medicine and Cellular Longevity2019
- — UVA-responsive ZnO@AKBA nano-particles provide a great potential for photoprotection, Materials Science and Engineering: C2019
Languages and skills
| Category | Details |
|---|---|
| English | Native Level in all modules (speaking, writing, reading, listening) |
| Deutsch | German Language (Deutsche Sprache) B2 level. Fluent in all modules (Reading, Writing, Speaking, and, listening) |
| Urdu | Native Level as a national language |
| Punjabi | Native level |
| Saraiki | Understand well, and, some basic conversation level |
| Chinese | Basic Level |
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